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Does Long-Term Cannabis Use Affect IQ?

Dr. Saira Zulfiqar, PharmD

Written by: Saira Zulfiqar

Updated on November 2, 2024

Does Long-Term Cannabis Use Affect IQ?

What is the Relationship Between Cannabis and Cognitive Decline?

In recent years, numerous studies have sought to explore the link between cannabis use and cognitive decline. A 44-year-long study in Denmark, which involved 5,162 male participants, found that long-term cannabis use did not significantly accelerate cognitive decline. In fact, the study revealed that cannabis users experienced a smaller reduction in cognitive abilities compared to non-users, with an average decrease of 6.2 IQ points for cannabis users, whereas non-users showed a slightly higher decline.

Interestingly, the study also indicated that even frequent cannabis users did not experience a significant difference in cognitive decline. This contrasts sharply with many mainstream stereotypes, which often associate cannabis use with a decline in IQ. The research team speculated that the smaller decline could be linked to characteristics of cannabis users, such as higher baseline IQs and education levels, which might counterbalance some of the potential negative effects of cannabis.

Moreover, some studies have found that active compounds in cannabis, such as THC (tetrahydrocannabinol), may have anti-aging effects on certain cognitive functions like memory and learning. These findings challenge the traditional view that cannabis use inevitably leads to cognitive damage, highlighting the complexity of the topic.

However, researchers caution that these findings do not imply that cannabis has no risk to cognitive functions. Especially in specific populations (e.g., middle-aged men), the conclusions of these studies may not be widely applicable. This underscores the need for further research into how cannabis affects different groups of people.

Does Cannabis Have a Positive Effect on Certain Cognitive Functions?

Although cannabis is typically viewed as having a negative impact on cognitive functions, recent studies have offered a different perspective. Some research has found that certain active compounds in cannabis, especially low doses of THC, may have a positive effect on specific cognitive functions. For instance, a study on mice demonstrated that low doses of THC could restore synaptic density in aging brains, improving learning and memory functions. These results suggest that appropriate doses of cannabis might possess anti-aging and cognitive-enhancing potential.

Human studies have also provided some support. A report published in the JAMA Network Open found that individuals with light to moderate cannabis use did not exhibit significant long-term negative effects on cognitive functions. On the contrary, some users even reported improvements in memory and attention, particularly when cannabis was used for pain relief, anxiety reduction, or sleep issues. Additionally, some cancer patients who received medical cannabis treatment reported clearer thinking and improved cognitive states.

More notably, another study found that patients who used medical cannabis long-term showed enhanced brain adaptability to certain symptoms without exhibiting the expected cognitive damage. This suggests that some chemical compounds in cannabis may have protective effects on cognitive abilities.

However, researchers emphasize that these positive effects typically depend on low doses and medical use of cannabis. High doses or recreational cannabis use may have adverse effects on short-term memory, attention, and executive functions. Therefore, when discussing the cognitive effects of cannabis, it’s important to differentiate between the purpose of use, dosage, and individual physiological conditions to better understand its potential positive and negative effects.

Where Do Cannabis Use and Stereotypes Clash?

For years, cannabis users have been labeled with negative stereotypes, such as “lower IQ,” “lazy,” or “slow thinking.” However, several recent studies have challenged these stereotypes. Denmark found that cannabis users experienced a smaller decline in cognitive abilities than non-users, and even after adjusting for potential confounding factors, this association held true. This finding directly contradicts the traditional view that cannabis inevitably damages intelligence.

Furthermore, a study from the National Institute on Drug Abuse (NIDA) in the United States found no causal relationship between cannabis use and IQ decline. The study specifically noted that individuals who showed IQ decline during adolescence might have already had a predisposition to lower IQ, unrelated to cannabis use. This further weakens the inherent bias linking cannabis to intellectual damage.

These research results suggest that the cognitive performance of cannabis users in some cognitive tests may be influenced by other factors, such as higher education levels or baseline IQ. Researchers have also proposed that certain lifestyle habits associated with cannabis use, such as increased consumption of tobacco or alcohol, may create confounding effects on cognitive outcomes. These findings prompt us to reconsider whether the conclusions drawn from stereotypes about cannabis users are based more on cultural biases than scientific evidence.

Nevertheless, the cognitive effects of cannabis are not without risks. Especially during adolescence, when the brain is still developing, frequent cannabis use can disrupt memory and learning abilities. However, the negative stereotypes about cannabis users clearly overlook the potential diversity of its effects on different individuals, revealing the profound conflict between existing perceptions and mainstream culture.

Why is Cannabis Use in Adolescents More Likely to Affect IQ?

Cannabis use in adolescents tends to have a more pronounced impact on IQ due to the rapid brain development that occurs during this period. Neuroscience research shows that key areas of the adolescent brain, particularly the prefrontal cortex responsible for memory, learning, and decision-making, are not fully mature during this time. At this stage, the brain’s neural circuits are more plastic and susceptible to external interference.

A notable study from New Zealand found that individuals who frequently used cannabis before the age of 18 and continued into adulthood experienced an average IQ decline of 8 points. This decline was significantly higher than that seen in occasional users or those who began using cannabis in adulthood. The study also pointed out that the most affected adolescent cannabis users were often dependent on cannabis, which may have contributed further to cognitive decline.

The IQ decline may not solely result from the direct effects of cannabis on the brain. Adolescents who use cannabis frequently often exhibit other behavioral changes, such as reduced study time, altered social circles, and increased risk of using other substances. In other words, the impact of cannabis may be the result of multiple factors, including its chemical effects on brain neurotransmission and the lifestyle changes associated with cannabis use.

Moreover, adolescents rely on the endocannabinoid system (ECS) for memory and attention processing, and THC in cannabis interacts with this system, potentially leading to short-term memory impairment and reduced learning efficiency. Due to their heightened brain sensitivity to external interference, these effects may be particularly pronounced in adolescents.

In summary, cannabis use in adolescence is particularly harmful because of its potential long-lasting effects on the developing brain. The resulting cognitive decline may not only impact academic performance but also affect future career development and quality of life. Preventative interventions for adolescents are crucial to avoid unnecessary long-term damage.

Does Frequency of Use and Dependency Play a Key Role?

The frequency of cannabis use and the degree of dependency are key factors in determining its impact on IQ and cognitive abilities. Research shows that occasional users of cannabis experience significantly less cognitive damage than heavy users.

For example, a long-term study in New Zealand found that individuals who used cannabis at least four times a week during adolescence and were diagnosed with cannabis dependence had an average IQ decline of 8 points. However, those who did not develop dependence showed no significant decline in IQ. The study also revealed that individuals who started using cannabis in adulthood, even at high frequencies, did not show notable IQ declines. This suggests that the timing of use, along with frequency and dependency, plays a critical role in determining the cognitive impact of cannabis.

Dependency is particularly important because frequent and high-dose use may have a more profound impact on the brain’s endocannabinoid system, which plays a key role in memory, mood regulation, and learning. The continuous interaction between THC and this system may lead to long-term changes in cognitive functions.

Moreover, frequent cannabis users tend to engage in other risk behaviors, such as poor study habits or lack of regular routines, which may further exacerbate cognitive decline. Some researchers have proposed that the combination of these lifestyle factors with heavy cannabis use may be a major cause of IQ decline.

However, some studies have questioned this conclusion. Some researchers argue that frequent cannabis users might already have cognitive or behavioral vulnerabilities that contribute to IQ decline, rather than cannabis use alone. Therefore, while frequency and dependency are important factors, other biological, psychological, and social factors must also be considered.

This complex relationship reminds us that when discussing cannabis’s effect on IQ, we should not attribute cognitive decline solely to frequency or dependency but should take a comprehensive approach by considering personal background, upbringing, and overall health.

Do Environmental and Behavioral Interactions Amplify the Effects of Cannabis?

Environmental and behavioral factors play a significant role in amplifying the cognitive effects of cannabis use, particularly in adolescents and young adults. In addition to the direct biological effects of cannabis, the user’s lifestyle, social circles, and socioeconomic environment can significantly influence the cognitive impact.

Research suggests that the environmental factors during adolescence are particularly critical in determining the negative impact of cannabis. Cannabis users often exhibit behavioral changes, such as reduced academic involvement, increased truancy, and a lack of proactive learning, which may exacerbate cognitive decline. For instance, adolescents who are addicted to cannabis often lack the motivation and focus to succeed in their studies, leading to learning deficiencies that can negatively affect IQ development.

Additionally, social circles play a vital role. Many cannabis users, especially young people, form social groups with other cannabis users, where cannabis consumption is normalized as a social activity. This often reinforces the habit and increases frequency, with cannabis becoming a coping mechanism for stress.

Moreover, this environment can also hinder personal growth and cognitive health. Adolescents in negative social environments may miss opportunities for positive psychological support, which is critical for cognitive development. The role of social support from family and friends is vital for maintaining cognitive health, and lacking this support in a cannabis-dominated social circle can diminish cognitive abilities over time.

Conclusion

While current research does not definitively prove that cannabis use will inevitably cause a decline in IQ, the effects on cognitive abilities remain concerning. Frequent use during adolescence, when the brain is still developing, can lead to significant cognitive damage. The negative impacts of cannabis are multifaceted, with biological effects interacting with environmental factors, behavioral changes, and social influences. Hence, a comprehensive understanding of cannabis’s impact on cognitive health requires considering a range of factors, including the timing and context of use. By addressing these issues in a nuanced manner, we can better understand the potential risks of cannabis use and protect cognitive function in vulnerable populations.

Dr. Saira Zulfiqar, PharmD
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